Androgen Replacement
Therapy

For males with low levels of testosterone due to disease or aging

It is a hormone treatment often prescribed to counter the effects of male hypogonadism or who for men who have lost their testicular function to disease, cancer, or other causes.

Why does testosterone (T) decrease with age?

Your body naturally produces less T as you age. According to an article in American Family Physician, the average male’s T production goes down by about 1 to 2 percent each year.

This is all part of a completely natural process that starts in your late 20s or early 30s:

  1. As you age, your testicles produce less T.
  2. Lowered testicular T causes your hypothalamus to produce less gonadotropin-releasing hormone (GnRH).
  3. Lowered GnRH causes your pituitary gland to makes less luteinizing hormone (LH).
  4. Lowered LH results in lowered overall T production.

This gradual decrease in T often doesn’t cause any noticeable symptoms. But a significant drop in T levels may cause:

  • low sex drive
  • fewer spontaneous erections
  • erectile dysfunction
  • lowered sperm count or volume
  • trouble sleeping
  • unusual loss of muscle and bone density
  • unexplained weight gain
How do I know if I have low T?

The only way to know whether you truly have low T is by seeing a healthcare provider for a testosterone level test. This is a simple blood test, and most providers require it before prescribing this treatment.

You may need to do the test several times because T levels are affected by various factors, such as:

  • diet
  • level of fitness
  • time of day the test is done
  • certain medications, like anticonvulsants and steroids

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